Home > Resource Centre > Beauty Complex > Ingredients Guides > Buyers Guides > Marine Collagen > Ingredient Information  > Marine collagen supplements with hyaluronic acid and vitamins

Marine collagen supplements with hyaluronic acid and vitamins | Which supplement combinations are the best?


Many people supplement with collagen to replace some of the collagen we naturally lose with age. Unfortunately, we lose 1-1.5% of our collagen each year after the age of 30. Collagen decline results in a loss of skin elasticity and hydration, contributing to the wrinkles and fine lines that we associate with age. Many supplements contain marine collagen for its high proportion of type I collagen fibres – the skin also contains primarily type I collagen.

In addition to marine collagen, many high-quality supplements contain additional ingredients that support the skin, hair, and nails. In fact, some ingredients even work synergistically with marine collagen. This article will cover how you can benefit from combining marine collagen with hyaluronic acid and certain vitamins, including vitamin C, vitamin E and biotin, into one marine collagen complex supplement.

Taking marine collagen and hyaluronic acid together

Hyaluronic acid is abundant in the skin and contributes to skin hydration – it can hold up to 6000 times its weight in water. As we age, we lose hyaluronic acid, so supplementation to replace it could be beneficial for dry skin.

Hyaluronic acid holds moisture in the skin and acts as a scavenger for free radicals. Free radicals can damage cellular structures and proteins, including collagen and fibroblast cells (the cells that produce collagen).

Marine collagen is typically taken with hyaluronic acid because of their combined benefits for the skin as we age. Hyaluronic acid helps to replenish what is lost with age, while hydrolysed collagen has been shown to stimulate both collagen synthesis and hyaluronic acid production.

Taking marine collagen and vitamin C together

Vitamin C is commonly found in collagen supplements, and this pairing is highly beneficial. Vitamin C is a co-factor for some enzymes involved in collagen production. Without vitamin C, normal collagen formation is impaired.

It is vital to take an adequate amount of vitamin C for the maintenance of healthy, normal skin; however, higher dosages of vitamin C may even be able to increase type I collagen production.

Another reason vitamin C is important for the skin is that it is an antioxidant – it scavenges free radicals that damage the skin, including collagen structures. Oxidative damage is the primary driving force behind tissue ageing, so supplementing with antioxidants is important for helping to maintain healthy skin, hair and nails.

Taking marine collagen and vitamin E

Similarly to vitamin C, vitamin E acts as an antioxidant and may also play a role in maintaining skin hydration . The most significant factor that affects skin ageing is oxidative damage; reactive oxygen species (ROS) that cause oxidative damage are generated naturally from metabolism and external factors such as UV radiation. Vitamin E is the predominant antioxidant present in the skin, so it is responsible for protecting the skin from much of this oxidative stress.

Oxidative stress can induce the breakdown of collagen structures, and fibroblasts are also damaged in the process. Therefore, protecting the skin from oxidative damage is crucial to maintaining collagen levels and skin elasticity.

In addition to its antioxidant properties, vitamin E can boost the efficacy of vitamin C eight-fold; this is because the vitamins can regenerate one another. As mentioned, vitamin C is closely linked to collagen formation, so it would also be beneficial to supplement with vitamin E when supplementing with vitamin C.

Read more about marine collagen and vitamin E supplements here.

Taking marine collagen and biotin

Biotin is an essential nutrient that we need to obtain from our diet. It is involved in many metabolic processes, including the formation of non-essential amino acids. Biotin deficiencies often present physically in the hair and nails; as a result, it has become a popular ingredient in food supplements for avoiding deficiencies that could affect the hair.

Additionally, hydrolysed marine collagen supplements contain many of the same amino acids found in keratin, the protein found in the hair and nails. Collagen supplementation may contribute some amino acids for keratin production.

Finally, since biotin is important for producing non-essential amino acids, it is essential for maintaining nail and hair health. Collagen production also requires essential and non-essential amino acids, which can be provided through collagen supplementation and with adequate amounts of biotin in the diet. For this reason, it may be beneficial to supplement with biotin and marine collagen together.

What vitamins go well with marine collagen?

There are plenty of ingredients that can support the function of marine collagen in the body or support the hair, skin and nails. The table below explores some ingredients that pair well with marine collagen and states their function concerning collagen synthesis, oxidative stress and anything else relevant to the skin, hair and nails. The table also suggests some other beneficial nutrient combinations.









Skin hydration

Phytoceramides and vitamin E, and vitamin C





Vitamin E and hyaluronic acid




May support the skin moisture barrier

Vitamin C, phytoceramides and hyaluronic acid




Maintenance of normal hair and nails

Selenium, Copper, Vitamin C and vitamin E.




Maintenance of normal hair, skin and nails

Biotin, copper, vitamin C and vitamin E




Maintenance of normal hair pigmentation and connective tissue

Biotin, Selenium vitamin C, and vitamin E




May contribute to maintaining the skin moisture barrier

Hyaluronic acid, vitamin E and vitamin C

When looking for an effective marine collagen complex supplement for the skin, hair and nails, it is vital to consider the pairing of ingredients. Refer to the table above and look for mutually beneficial ingredient combinations in the nutritional information of your supplement. Beauty Complex is a marine collagen powder supplement formulated to effectively deliver eight active ingredients to support the skin, hair and nails. Each Beauty Complex daily sachet includes a carefully chosen dose of marine collagen hydrolysate, vitamin C, vitamin E, hyaluronic acid, biotin, Selenium, Copper and phytoceramides. This potent combination of ingredients is designed to support the skin, the hair and the nails without the guesswork of supplement mixing.


  1. Skin collagen through the lifestages: importance for skin health and beauty

  2. Cosmetic Potential of Marine Fish Skin Collagen

  3. Ingestion of an Oral Hyaluronan Solution Improves Skin Hydration, Wrinkle Reduction, Elasticity, and Skin Roughness: Results of a Clinical Study

  4. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials

  5. Skin Photoaging and the Role of Antioxidants in Its Prevention

  6. The Roles of Vitamin C in Skin Health

  7. High-dose vitamin C supplementation accelerates the Achilles tendon healing in healthy rats

  8. Vitamin E in human skin: Organ-specific physiology and considerations for its use in dermatology

  9. A review of skin ageing and its medical therapy

  10. Anti-wrinkling effects of the mixture of vitamin C, vitamin E, pycnogenol and evening primrose oil, and molecular mechanisms on hairless mouse skin caused by chronic ultraviolet B irradiation

  11. Vitamin C in dermatology

  12. A Review of the Use of Biotin for Hair Loss

  13. Improving Skin Hydration and Age-related Symptoms by Oral Administration of Wheat Glucosylceramides and Digalactosyl Diglycerides: A Human Clinical Study